My Most recent one is from Chrno Crusade
-----The whole scene with Chrno and Rosette sitting on the porch of that abandoned house at the end.
Have to say I couldn't help but cry.
I SUCK Cant make Banners!
In Flame of Recca at the end of the manga series when Recca's girl died
One of the most touching scenes was in Blue Gender in the end when Yugi tells Marlene that she cant acompany him into the glowing pillar of light to comune with the earth cause it might harm her, but then she says they must stick together "not just for me, but for our child." revealing that she is pregnate. This scene i rank as the most touching anime scene i have ever seen.
Onepiece - when luffy's pirate crew have to depart with going merry....what a painful option to burn your own nakama......:'(
mine would be the last OVA of Kenshin. although i didnt feel that sad but my i loled so hard when my cousin burst into tears
another good one is in the manga/anime Suzuka:
when yamato confesses to suzuka the second time and she runs away to honoka's shrine. honoka and suzuka have a fight over yamato and kazuki and their feelings and it just makes you cry. and then after that when suzuka and yamato go to kazuki's grave and she admits that she likes yamato alot. the whole progression of this is amazing.