Soooo, almost every reply here of the saddest death is that of Hughes (or is is it all? Owned.....)
Yes, Hughes was the saddest one for me as well, tears absolutely flooded my eyes when I witnessed the scne, though I rubbed it before the tears had the chance to roll down.
Nina's death, or rather, the relevation of it, came in second(though not close enough)
Cooles for me was lust's, Greed's came in the second, though he get totally owned by the Fuhrer....
Both deaths refer to the manga version.
~The love in our hearts are the only beautiful, never-changing myth~